MODAG focuses on research and development of therapeutics and diagnostics for neurodegenerative diseases. It is a privately held company located in Wendelsheim, Germany with additional Research & Development facilities in Munich and Göttingen. MODAG’s innovative approach offers a unique combination of early diagnosis and targeted disease-modifying therapies for severe neurological disorders. MODAG’s collaborations with top-tier US and European research institutions, combined with the interdisciplinary research and development expertise of the founder’s and the management team, provide ideal conditions for the accelerated implementation into clinical applications. Built upon an extensive portfolio of patented active compounds, MODAG is developing a new oligomer modulator for Multiple System Atrophy (MSA) and other synucleinopathies such as Parkinson’s disease (PD) with the potential to deliver novel disease-odifying, first-in-class drugs with the potential to halt progression.

MODAG aims to provide a novel approach for treating neurodegenerative diseases by combining targeted small molecule therapeutics with the right diagnostic tools. Our first objective is to demonstrate clinical proof-of-concept with our lead compound anle138b in Multiple System Atrophy (MSA) seeking to halt the progression and provide a first disease-modifying therapeutic. This success will allow us to apply our technology to similar diseases such as Parkinson’s and other synucleinopathies with the goal of dissolving disease-related intra-cellular oligomers, thereby reducing their toxic properties. MODAG is comprised of experts in the clinical research and neurodegenerative disease space and supported by grants from leading patient organizations including the Michael J. Fox Foundation, Cure Parkinson’s Trust and Parkinson’s UK.