{"id":25878,"date":"2025-12-17T09:24:48","date_gmt":"2025-12-17T08:24:48","guid":{"rendered":"https:\/\/www.izb-online.de\/?p=25878"},"modified":"2025-12-18T10:36:36","modified_gmt":"2025-12-18T09:36:36","slug":"t-curx-secures-20m-series-a-to-advance-non-viral-car-t-platform","status":"publish","type":"post","link":"https:\/\/www.izb-online.de\/en\/izb-biotech-news\/t-curx-secures-20m-series-a-to-advance-non-viral-car-t-platform\/","title":{"rendered":"T-CURX announces $20M Series A first closing led by BiomedVC to fund pipeline of clinical-stage CAR-T programs and advance proprietary non-viral in vivo CAR-T platform"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row el_class=&#8221;gco-magazine-container&#8221;][vc_column el_class=&#8221;bildspalte&#8221;][vc_row_inner][vc_column_inner offset=&#8221;vc_col-lg-12 vc_col-md-12&#8243;][vc_column_text css=&#8221;&#8221; el_class=&#8221;gco-magazine&#8211;title&#8221;]<\/p>\n<h1>T-CURX announces $20M Series A first closing led by BiomedVC to fund pipeline of clinical-stage CAR-T programs and advance proprietary non-viral in vivo CAR-T platform<\/h1>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221; el_class=&#8221;gco-magazine-lead&#8221;]Financing supports clinical development of non-viral CAR-T therapies in AML and solid tumors and advances a scalable in vivo CAR-T generation platform.[\/vc_column_text][vc_column_text css=&#8221;&#8221; el_class=&#8221;gco-magazine&#8211;post-date&#8221;]December, 2025[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner el_class=&#8221;two-columns&#8221; el_id=&#8221;corona-ausblenden&#8221;][vc_column_inner el_class=&#8221;bild-zwei-spalten-links&#8221;][vc_single_image image=&#8221;6283&#8243; img_size=&#8221;full&#8221;][vc_column_text el_class=&#8221;gco-magazine-copyright&#8221;]\u00a9 Pieris[\/vc_column_text][vc_column_text el_class=&#8221;gco-magazine-picture-discription&#8221;]The Lungs[\/vc_column_text][vc_single_image image=&#8221;6285&#8243; img_size=&#8221;full&#8221;][vc_column_text el_class=&#8221;gco-magazine-copyright&#8221;]\u00a9 Pieris[\/vc_column_text][vc_column_text el_class=&#8221;gco-magazine-picture-discription&#8221;]<strong>Stephen S. Yoder<\/strong>, CEO, Pieris Pharmaceuticals Inc.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner][vc_single_image image=&#8221;25881&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221; el_class=&#8221;gco-magazine-copyright&#8221;]\u00a9 iStock \/ Avosb[\/vc_column_text][vc_column_text css=&#8221;&#8221; el_class=&#8221;gco-magazine-picture-discription&#8221;]T-CURX announces $20M Series A first closing led by BiomedVC[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner el_class=&#8221;gco-magazine&#8211;quote&#8221; css=&#8221;.vc_custom_1611310713611{margin-top: 33px !important;}&#8221;][vc_column_inner][vc_column_text css=&#8221;&#8221;]<\/p>\n<h6 style=\"text-align: center;\">\u201cWe are very much looking forward to support T-CURX to achieve all of their therapeutic and commercial ambitions.\u201d<\/h6>\n<p style=\"text-align: center;\">Aristotelis Nastos, Managing Partner and investment director at lead-investor BiomedVC<\/p>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner el_class=&#8221;gco-magazine-container&#8211;copy&#8221; css=&#8221;.vc_custom_1591795890737{margin-top: 21px !important;}&#8221;][vc_column_inner][vc_column_text css=&#8221;&#8221;]IZB-based start-up T-CURX GmbH (T-CURX) announced on December 17, 2025, the first closing of a $ 20M (\u20ac 17.7M) Series A financing with a syndicate of European and Asian investors for accelerating clinical development of T-CURX non-viral clinical CAR-T therapies in AML and solid tumor indications, as well as advancing T-CURX proprietary non-viral technologies for in vivo CAR-T generation.<\/p>\n<p>The Series A syndicate was led by BiomedVC and included Bayern Kapital, HighLight Capital (HLC), and i&amp;iBio Fund, as additional investors along with existing and new individual investors.<\/p>\n<p>Ulf Grawunder, PhD, co-founder and CEO of T-CURX, commented on the closing of this Series A financing round for T-CURX:\u201cI am very excited that T-CURX attracted such a high-profile, international investor\u2019s syndicate, led by BiomedVC, for financing T-CURX`s non-clinical and clinical CAR-T technologies and CAR-T pipeline programs, respectively. It is a testament of the high quality of T-CURX data and the promise of our non-clinical and clinical non-viral CAR-T pipeline in AML &amp; CLL and solid tumor indications going after novel targets. It also highlights the high value of our unique approach to leverage non-viral CAR-vector and LNP technologies for highly economical and scalable in vivo CAR-T generation, in order to \u201cdemocratize\u201d CAR-T therapies for patients globally.\u201d<\/p>\n<p>Aristotelis Nastos, PhD, Managing Partner and investment director at lead-investor BiomedVC adds:<br \/>\n\u201cI am thrilled about leading a highly dedicated international syndicate of early-stage investors from Europe and Asia in this Series A financing for T-CURX. We were deeply impressed by the data on non-viral CAR-T product and technology development at T-CURX, the track-record and experience of T-CURX Founder\u2019s and Management team and the promise of T-CURX non-viral CAR-T technolgies hold for making CAR-T therapies accessible and affordable for many cancer patients globally. We are very much looking forward to support T-CURX to achieve all of their therapeutic and commercial ambitions\u201d<\/p>\n<p><strong>T-CURX<\/strong> is a German Biotech company located in W\u00fcrzburg and Munich, Germany, spun-out of the laboratory of its co-founder, Prof. Michael Hudecek, University of W\u00fcrzburg, who is a European KOL and pioneer in the development and clinical translation of <strong>non-viral CAR-T cell therapies to target various types of cancer<\/strong>.<\/p>\n<p><strong>About T-CURX<\/strong><br \/>\nT-CURX is a privately owned, German Biotech company based in W\u00fcrzburg founded in 2017 with the vision of bringing next-generation CAR-T cell therapies manufactured with cost-effective and highly scalable non-viral CAR-T cell technologies to more cancer patients in need of more effective cancer therapies. T-CURX was spun out of the laboratory of T-CURX co-founder Prof. Michael Hudecek at the University of W\u00fcrzburg and is led by Ulf Grawunder, PhD, a seasoned serial entrepreneur as CEO, who is also one of the co-founders. T-CURX leverages a portfolio of proprietary non-viral CAR-T technologies for scalable and cost-effective CAR-T manufacturing based on virus-free, Sleeping-beauty transposon gene transfer into patient\u2019s T cells. For more information about T-CURX visit the web-site <a href=\"https:\/\/www.t-curx.com\/\" target=\"_blank\" rel=\"noopener\">www.t-curx.com<\/a><\/p>\n<p><strong>About BiomedVC <\/strong><br \/>\nBiomedVC is is a leading Swiss early-stage VC at the center of European biotech. BiomedVC builds companies around the most intriguing innovation. We strive to enable founders and their ideas. We work together on a basis of equality &#8211; as a team and with entrepreneurs. We focus on scientific excellence, building strong companies to create medical and commercial value and bring new medicines to market that improve patient\u2019s lives.<\/p>\n<p><strong>For further information:<\/strong><br \/>\nUlf Grawunder, CEO<br \/>\nE-mail: <a href=\"mailto:ulf@t-curx.com\">ulf@t-curx.com<\/a><\/p>\n<p><strong>For media enquiries:<\/strong><br \/>\nPhone: +49-(0)-931-250-99-712<br \/>\nE-mail: <a href=\"mailto:pr@t-curx.com\">pr@t-curx.com<\/a>[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1583761043671{background-color: #1e73be !important;}&#8221; el_class=&#8221;redaktionell&#8221;][\/vc_column_text][\/vc_column_inner][\/vc_row_inner]\n\n  <div class=\"gco-sc-company\" data-gco-companty-debug=\"should render logo\">\n    <a  href=\"https:\/\/www.izb-online.de\/en\/unternehmen\/t-curx\/\" class=\"gco-sc-company__primary-action\">\n              <div class=\"gco-sc-company__logo gco-sc-company__logo--as-bground\" style=\"background-image: url(https:\/\/www.izb-online.de\/wp-content\/uploads\/2022\/12\/T-Curx-1.jpg)\">\n                  <\/div>\n      \n      <div class=\"gco-sc-company__name\">\n        T-CURX      <\/div>\n\n      <ul class=\"gco-sc-company__contact\">\n                  <li class=\"gco-sc-company__contact-item gco-sc-company__contact-item--street\">\n            Friedrich-Bergius-Ring 15          <\/li>\n        \n                  <li class=\"gco-sc-company__contact-item gco-sc-company__contact-item--city\">\n            97076 W\u00fcrzburg          <\/li>\n        \n        \n                  <li class=\"gco-sc-company__contact-item gco-sc-company__contact-item--fon\">\n            <span class=\"gco-sc-company__contact-item-label\">\n              Phone:            <\/span>\n            <span class=\"gco-sc-company__contact-item-value\">\n              +49-(0)-931-250-99-712            <\/span>\n          <\/li>\n        \n              <\/ul>\n    <\/a>\n    <ul class=\"gco-sc-company__contact gco-sc-company__contact--internet\">\n              <li class=\"gco-sc-company__contact-item gco-sc-company__contact-item--website-email\">\n          info@t-curx.com        <\/li>\n      \n              <li class=\"gco-sc-company__contact-item gco-sc-company__contact-item--website-link\">\n          <a href=\"https:\/\/www.t-curx.com\">\n            www.t-curx.com          <\/a>\n        <\/li>\n          <\/ul>\n  <\/div>\n[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p><span class=\"gco-utils-excerpt\" data-debug-trim-excerpt=\"151\"><span class=\"gco-utils-excerpt__part-xs\">Financing supports clinical development of non-viral CAR-T therapies in AML and solid<\/span><span class=\"gco-utils-excerpt__part-xl\"> tumors and advances a scalable in vivo CAR-T generation<\/span><\/span><\/p>\n","protected":false},"author":1,"featured_media":25879,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1539,286,6402],"tags":[],"class_list":["post-25878","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-izb-biotech-news","category-izb-news","category-top-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.1 (Yoast SEO v28.1) - 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