{"id":16053,"date":"2021-02-24T13:43:08","date_gmt":"2021-02-24T12:43:08","guid":{"rendered":"https:\/\/www.izb-online.de\/?p=16053"},"modified":"2021-02-24T13:43:08","modified_gmt":"2021-02-24T12:43:08","slug":"sirion-biotech-announces-collaboration-with-sanofi-to-innovate-gene-therapy-treatments-with-improved-adeno-associated-virus-capsids","status":"publish","type":"post","link":"https:\/\/www.izb-online.de\/en\/sirion-biotech-announces-collaboration-with-sanofi-to-innovate-gene-therapy-treatments-with-improved-adeno-associated-virus-capsids\/","title":{"rendered":"SIRION Biotech Announces Collaboration with Sanofi to Innovate Gene Therapy Treatments with Improved Adeno-Associated Virus Capsids"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row el_class=&#8221;gco-magazine-container&#8221;][vc_column el_class=&#8221;bildspalte&#8221;][vc_row_inner][vc_column_inner offset=&#8221;vc_col-lg-12 vc_col-md-12&#8243;][vc_column_text el_class=&#8221;gco-magazine&#8211;title&#8221;]<\/p>\n<h1>SIRION Biotech Announces Collaboration with Sanofi to Innovate Gene Therapy Treatments with Improved Adeno-Associated Virus Capsids<\/h1>\n<p>[\/vc_column_text][vc_column_text el_class=&#8221;gco-magazine-lead&#8221;]SIRION Biotech GmbH, a world leader in viral vector-based gene delivery technologies for gene &amp; cell therapy, announced on February 23, 2021 that it signed a license and collaboration agreement with Sanofi, a global biopharmaceutical company, to develop improved tissue-selective adeno-associated virus (AAV) vectors to realize effective gene therapy treatments for disorders affecting major human organs.[\/vc_column_text][vc_column_text el_class=&#8221;gco-magazine&#8211;post-date&#8221;]February 2021[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner][vc_single_image image=&#8221;16046&#8243; img_size=&#8221;full&#8221;][vc_column_text el_class=&#8221;gco-magazine-copyright&#8221;]\u00a9 Sirion Biotech GmbH[\/vc_column_text][vc_column_text el_class=&#8221;gco-magazine-picture-discription&#8221;]Dr. Christian Thirion, CEO Sirion Biotech GmbH[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner el_class=&#8221;gco-magazine&#8211;quote&#8221; css=&#8221;.vc_custom_1611310713611{margin-top: 33px !important;}&#8221;][vc_column_inner][vc_column_text]<\/p>\n<h6 style=\"text-align: center;\">\u201cThis partnership adds to our expanding toolbox of technologies in the important, emerging area of gene therapeutics.\u201d<\/h6>\n<p style=\"text-align: center;\">Dr. Christian Mueller<br \/>\nglobal head of genomic medicine at Sanofi.<\/p>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner el_class=&#8221;gco-magazine-container&#8211;copy&#8221; css=&#8221;.vc_custom_1591795890737{margin-top: 21px !important;}&#8221;][vc_column_inner][vc_column_text]SIRION Biotech GmbH, a world leader in viral vector-based gene delivery technologies for gene &amp; cell therapy, announced on February 23, 2021 that it signed a license and collaboration agreement with Sanofi, a global biopharmaceutical company, to develop improved tissue-selective adeno-associated virus (AAV) vectors to realize effective gene therapy treatments for disorders affecting major human organs.<\/p>\n<p>AAV vectors are a promising and clinically validated gene delivery platform for the potential treatment of a variety of human diseases. Sanofi, together with SIRION Biotech and Prof. Dirk Grimm, a world-renowned and pioneering scientist in the field of AAV biology and application working at Heidelberg University Hospital (Germany), will combine their proprietary technology platforms to create a next generation of AAV vectors. The goal of this collaboration is to develop new and modified AAV capsids that exhibit a safe product profile with improved specificity and higher gene delivery efficiency.<\/p>\n<p>\u201cThis partnership adds to our expanding toolbox of technologies in the important, emerging area of gene therapeutics,\u201d said Dr. Christian Mueller, global head of genomic medicine at Sanofi. \u201cLeveraging our expertise in virus-based vaccine and viral vector manufacturing together with Prof. Grimm\u2019s cutting-edge AAV capsid evolution technology and SIRION\u2019s expertise and capabilities in AAV vector manufacturing will allow us to better address unmet medical needs and open new frontiers for drug discovery in genomic medicine.\u201d<\/p>\n<p>\u201cWe are delighted to be collaborating with Sanofi,\u201d stated Christian Thirion, Ph.D., CEO and Co\u2011founder of SIRION. \u201cSanofi is an ideal partner with decades-long experience in treating a multitude of disorders and exploring viral vectors as a therapeutic modality. AAV vectors with improved efficacy can enable quickly entering into clinical trials with efficient, safe low doses and scalable therapeutic candidates and can expand the impact of gene therapies.\u201d Sabine Ott, Senior Vice President BD &amp; Licensing at SIRION added: \u201cWe believe that through this exclusive partnership with Sanofi within these large disease fields, AAV-based gene therapies will provide novel treatment options to many millions of patients worldwide suffering from these diseases\u201d.<\/p>\n<p><strong>About SIRION Biotech GmbH<br \/>\n<\/strong>SIRION Biotech was founded in 2005 with the goal to spark a new generation of viral vector technologies for gene and cell therapy as well as vaccine development. SIRION evolves novel therapeutic viral vectors and uses proprietary technology platforms based on lenti-, adeno-, and adeno-associated viruses, to expedite its partners\u2019 advances in drug development. For additional information, please visit\u00a0<a href=\"http:\/\/www.sirion-biotech.com\">www.sirion-biotech.com<\/a>.<\/p>\n<p><strong>\u00a0<\/strong>[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1583761043671{background-color: #1e73be !important;}&#8221; el_class=&#8221;redaktionell&#8221;][\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p><span class=\"gco-utils-excerpt\">Joining forces to develop gene therapies for multiple life-threatening disorders<\/span><\/p>\n","protected":false},"author":8,"featured_media":16044,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1539,286,6402],"tags":[],"class_list":["post-16053","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-izb-biotech-news","category-izb-news","category-top-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.1 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>SIRION Biotech Announces Collaboration with Sanofi to Innovate Gene Therapy Treatments with Improved Adeno-Associated Virus Capsids<\/title>\n<meta name=\"description\" content=\"Joining forces to develop gene therapies for multiple life-threatening disorders\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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