{"id":21516,"date":"2022-12-19T10:56:35","date_gmt":"2022-12-19T09:56:35","guid":{"rendered":"https:\/\/www.izb-online.de\/unternehmen\/t-curx\/"},"modified":"2024-07-31T15:13:50","modified_gmt":"2024-07-31T13:13:50","slug":"t-curx","status":"publish","type":"gco_companies","link":"https:\/\/www.izb-online.de\/en\/unternehmen\/t-curx\/","title":{"rendered":"T-CURX"},"content":{"rendered":"

[vc_row][vc_column][\/vc_column][\/vc_row][vc_row el_class=”container-inner”][vc_column][vc_row_inner][vc_column_inner el_class=”gco-tmpl-company__image-column” width=”1\/2″ offset=”vc_col-lg-4 vc_col-md-4″][vc_single_image image=”21508″ img_size=”full” el_class=”gco-tmpl-company__image”][vc_column_text el_class=”gco-tmpl-company__image-info-copyright”]T-CURX GmbH[\/vc_column_text][vc_column_text el_class=”gco-tmpl-company__image-info-desc”]Dr. Ulf Grawunder, CEO[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″ offset=”vc_col-lg-8 vc_col-md-8″][vc_column_text el_class=”gco-company-post-heading”]<\/p>\n

About T-CURX<\/h3>\n

[\/vc_column_text][vc_column_text css=””]T-CURX is a biopharmaceutical start-up company based in W\u00fcrzburg and Munich, focusing on the development and commercialization of next-generation CAR-T cell therapies for cancer indications with high medical needs. The proprietary CAR-T technologies were developed in the laboratory of co-founder Prof. Michael Hudecek at the University Hospital W\u00fcrzburg and involve a non-viral, transposon-based gene transfer of the CAR receptor into the patient’s autologous T cells. The non-viral production of CAR-T cells is a key unique selling point for a fast, cost-efficient, safe, and patient-centered manufacturing method, including the production of CAR-T cells directly at the patient’s bedside. In future, the liponanoparticle technology developed by T-CURX will also be used for the targeted administration of the genetic components. T-CURX utilises its innovative manufacturing approach to develop a clinical pipeline with novel targets for hematological and solid tumors. T-CURX’s technologies have already been validated in an academically initiated Phase I clinical study. The company’s first proprietary clinical program is ready for clinical trial submission by the end of the year.[\/vc_column_text][vc_column_text el_class=”gco-company-post-heading”]<\/p>\n

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What is your motivation?<\/h3>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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The success rates of approved CAR-T cell therapies for terminally ill patients, who often have no other treatment options, are impressive. However, the costs of this therapy modality need to decrease significantly, and the prerequisites for scalable and decentralized production must be established. This is the only way to create access to autologous CAR-T products for the benefit of all patients, including countries where these transformative therapies are currently inaccessible. Our approach has the potential to revolutionise the field of CAR-T therapies and can be seen as a true democratisation of CAR-T therapies.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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