{"id":1645,"date":"2020-03-12T10:22:35","date_gmt":"2020-03-12T09:22:35","guid":{"rendered":"http:\/\/wordpress.p545550.webspaceconfig.de\/gco_companies\/modag-gmbh\/"},"modified":"2021-03-16T15:07:59","modified_gmt":"2021-03-16T14:07:59","slug":"modag-gmbh","status":"publish","type":"gco_companies","link":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/","title":{"rendered":"Modag GmbH"},"content":{"rendered":"

[vc_row][vc_column][\/vc_column][\/vc_row][vc_row el_class=”container-inner”][vc_column][vc_row_inner][vc_column_inner el_class=”gco-tmpl-company__image-column” width=”1\/2″ offset=”vc_col-lg-4 vc_col-md-4″][vc_single_image image=”15801″ img_size=”full” el_class=”gco-tmpl-company__image”][vc_column_text el_class=”gco-tmpl-company__image-info-copyright”]Modag[\/vc_column_text][vc_column_text el_class=”gco-tmpl-company__image-info-desc”]Dr. Torsten Matthias, CEO; Prof. Dr. Armin Giese, Wissenschaftlicher Gesch\u00e4ftsf\u00fchrer \/ Scientific Director; Prof. Dr. Johannes Levin, CMO[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″ offset=”vc_col-lg-8 vc_col-md-8″][vc_column_text el_class=”gco-company-post-heading”]<\/p>\n

About Modag<\/h3>\n

[\/vc_column_text][vc_column_text]<\/p>\n

MODAG focuses on research and development of therapeutics and diagnostics for neurodegenerative diseases. It is a privately held company located in Wendelsheim, Germany with additional Research & Development facilities in Munich and G\u00f6ttingen. MODAG\u2019s innovative approach offers a unique combination of early diagnosis and targeted disease-modifying therapies for severe neurological disorders. MODAG\u2019s collaborations with top-tier US and European research institutions, combined with the interdisciplinary research and development expertise of the founder\u2019s and the management team, provide ideal conditions for the accelerated implementation into clinical applications. Built upon an extensive portfolio of patented active compounds, MODAG is developing a new oligomer modulator for Multiple System Atrophy (MSA) and other synucleinopathies such as Parkinson\u2019s disease (PD) with the potential to deliver novel disease-odifying, first-in-class drugs with the potential to halt progression.<\/p>\n

[\/vc_column_text][vc_column_text el_class=”gco-company-post-heading”]<\/p>\n

\n
\n
\n
\n

What is your motivation?<\/h3>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/vc_column_text][vc_column_text]<\/p>\n

\n
\n
\n
\n

MODAG aims to provide a novel approach for treating neurodegenerative diseases by combining targeted small molecule therapeutics with the right diagnostic tools. Our first objective is to demonstrate clinical proof-of-concept with our lead compound anle138b in Multiple System Atrophy (MSA) seeking to halt the progression and provide a first disease-modifying therapeutic. This success will allow us to apply our technology to similar diseases such as Parkinson\u2019s and other synucleinopathies with the goal of dissolving disease-related intra-cellular oligomers, thereby reducing their toxic properties. MODAG is comprised of experts in the clinical research and neurodegenerative disease space and supported by grants from leading patient organizations including the Michael J. Fox Foundation, Cure Parkinson\u2019s Trust and Parkinson\u2019s UK.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/2″ offset=”vc_col-lg-4 vc_col-md-4″][\/vc_column][vc_column width=”1\/2″ el_class=”gco-tmpl-company-quote” offset=”vc_col-lg-8 vc_col-md-8″][vc_column_text el_class=”gco-tmpl-company-quote__text”]\u201cThe IZB provides the perfect infrastructure for MODAG, immediate vicinity to the high-tech campus Gro\u00dfhadern \/ Martinsried and outstanding networking opportunities.\u201d[\/vc_column_text][vc_column_text el_class=”gco-tmpl-company-quote__source”]Dr. Torsten Matthias, CEO; Prof. Dr. Armin Giese, Wissenschaftlicher Gesch\u00e4ftsf\u00fchrer \/ Scientific Director; Prof. Dr. Johannes Levin, CMO[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column offset=”vc_hidden-lg vc_hidden-md vc_hidden-sm vc_hidden-xs”][vc_row_inner][vc_column_inner][vc_column_text el_class=”text-unternehmen”]MODAG GmbH was founded out of the Center for Neuropathology at LMU Munich (Prof. Dr. Armin Giese) and the Max Planck Institute for Biophysical Chemistry G\u00f6ttingen (Prof. Dr. Christian Griesinger).<\/p>\n

The company develops small molecule therapeutics that specifically inhibit pathological oligomeric protein aggregates that are central to the pathogenesis of neurodegenerative diseases such as Parkinson’s and Alzheimer’s. The great advantage of this small molecule approach over antibodies is the oral bioavailability, the very good brain movement and the effect in the cytoplasm of nerve cells in which these oligomers are formed. Last year (2019), MODAG successfully closed a financing round of EUR 12 million. The MODAG active ingredient anle138b has been in a clinical phase 1 study since the end of 2019. In addition, on the basis of its patented substance portfolio, MODAG develops synuclein-specific PET tracers as well as the highly sensitive qRT-QuIC method for the diagnostic detection of disease-specific synuclein aggregates in the brain and CSF of patients. Nachweis krankheitsspezifischer Synuclein-Aggregate im Hirn und Liquor von Patienten.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"featured_media":1644,"template":"","meta":{"_links_to":"","_links_to_target":""},"company-categories":[205],"class_list":["post-1645","gco_companies","type-gco_companies","status-publish","has-post-thumbnail","hentry","company-categories-startups-en"],"yoast_head":"\nModag GmbH - Innovations- und Gr\u00fcnderzentrum Biotechnologie IZB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Modag GmbH\" \/>\n<meta property=\"og:description\" content=\"ModagDr. Torsten Matthias, CEO; Prof. Dr. Armin Giese, Wissenschaftlicher Gesch\u00e4ftsf\u00fchrer \/ Scientific Director; Prof. Dr. Johannes Levin, CMO About Modag\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/\" \/>\n<meta property=\"og:site_name\" content=\"Innovations- und Gr\u00fcnderzentrum Biotechnologie IZB\" \/>\n<meta property=\"article:modified_time\" content=\"2021-03-16T14:07:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.izb-online.de\/wp-content\/uploads\/2020\/03\/Modag_Start-Up-im-IZB-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"400\" \/>\n\t<meta property=\"og:image:height\" content=\"80\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/unternehmen\\\/modag-gmbh\\\/\",\"url\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/unternehmen\\\/modag-gmbh\\\/\",\"name\":\"Modag GmbH - Innovations- und Gr\u00fcnderzentrum Biotechnologie IZB\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/unternehmen\\\/modag-gmbh\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/unternehmen\\\/modag-gmbh\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.izb-online.de\\\/wp-content\\\/uploads\\\/2020\\\/03\\\/Modag_Start-Up-im-IZB-1.jpg\",\"datePublished\":\"2020-03-12T09:22:35+00:00\",\"dateModified\":\"2021-03-16T14:07:59+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/unternehmen\\\/modag-gmbh\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.izb-online.de\\\/en\\\/unternehmen\\\/modag-gmbh\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/unternehmen\\\/modag-gmbh\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.izb-online.de\\\/wp-content\\\/uploads\\\/2020\\\/03\\\/Modag_Start-Up-im-IZB-1.jpg\",\"contentUrl\":\"https:\\\/\\\/www.izb-online.de\\\/wp-content\\\/uploads\\\/2020\\\/03\\\/Modag_Start-Up-im-IZB-1.jpg\",\"width\":400,\"height\":80},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/unternehmen\\\/modag-gmbh\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Startups im IZB\",\"item\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/company-categories\\\/startups-en\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Modag GmbH\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/\",\"name\":\"Innovations- und Gr\u00fcnderzentrum Biotechnologie IZB\",\"description\":\"Innovations- und Gr\u00fcnderzentrum Biotechnologie\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/#organization\",\"name\":\"F\u00f6rdergesellschaft IZB mbH\",\"url\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.izb-online.de\\\/wp-content\\\/uploads\\\/2020\\\/06\\\/izb-logo.svg\",\"contentUrl\":\"https:\\\/\\\/www.izb-online.de\\\/wp-content\\\/uploads\\\/2020\\\/06\\\/izb-logo.svg\",\"width\":1,\"height\":1,\"caption\":\"F\u00f6rdergesellschaft IZB mbH\"},\"image\":{\"@id\":\"https:\\\/\\\/www.izb-online.de\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Modag GmbH - Innovations- und Gr\u00fcnderzentrum Biotechnologie IZB","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/","og_locale":"en_US","og_type":"article","og_title":"Modag GmbH","og_description":"ModagDr. Torsten Matthias, CEO; Prof. Dr. Armin Giese, Wissenschaftlicher Gesch\u00e4ftsf\u00fchrer \/ Scientific Director; Prof. Dr. Johannes Levin, CMO About Modag","og_url":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/","og_site_name":"Innovations- und Gr\u00fcnderzentrum Biotechnologie IZB","article_modified_time":"2021-03-16T14:07:59+00:00","og_image":[{"width":400,"height":80,"url":"https:\/\/www.izb-online.de\/wp-content\/uploads\/2020\/03\/Modag_Start-Up-im-IZB-1.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/","url":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/","name":"Modag GmbH - Innovations- und Gr\u00fcnderzentrum Biotechnologie IZB","isPartOf":{"@id":"https:\/\/www.izb-online.de\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/#primaryimage"},"image":{"@id":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/#primaryimage"},"thumbnailUrl":"https:\/\/www.izb-online.de\/wp-content\/uploads\/2020\/03\/Modag_Start-Up-im-IZB-1.jpg","datePublished":"2020-03-12T09:22:35+00:00","dateModified":"2021-03-16T14:07:59+00:00","breadcrumb":{"@id":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/#primaryimage","url":"https:\/\/www.izb-online.de\/wp-content\/uploads\/2020\/03\/Modag_Start-Up-im-IZB-1.jpg","contentUrl":"https:\/\/www.izb-online.de\/wp-content\/uploads\/2020\/03\/Modag_Start-Up-im-IZB-1.jpg","width":400,"height":80},{"@type":"BreadcrumbList","@id":"https:\/\/www.izb-online.de\/en\/unternehmen\/modag-gmbh\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.izb-online.de\/en\/"},{"@type":"ListItem","position":2,"name":"Startups im IZB","item":"https:\/\/www.izb-online.de\/en\/company-categories\/startups-en\/"},{"@type":"ListItem","position":3,"name":"Modag GmbH"}]},{"@type":"WebSite","@id":"https:\/\/www.izb-online.de\/en\/#website","url":"https:\/\/www.izb-online.de\/en\/","name":"Innovations- und Gr\u00fcnderzentrum Biotechnologie IZB","description":"Innovations- und Gr\u00fcnderzentrum Biotechnologie","publisher":{"@id":"https:\/\/www.izb-online.de\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.izb-online.de\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.izb-online.de\/en\/#organization","name":"F\u00f6rdergesellschaft IZB mbH","url":"https:\/\/www.izb-online.de\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.izb-online.de\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.izb-online.de\/wp-content\/uploads\/2020\/06\/izb-logo.svg","contentUrl":"https:\/\/www.izb-online.de\/wp-content\/uploads\/2020\/06\/izb-logo.svg","width":1,"height":1,"caption":"F\u00f6rdergesellschaft IZB mbH"},"image":{"@id":"https:\/\/www.izb-online.de\/en\/#\/schema\/logo\/image\/"}}]}},"gco_companies_contact_fax":"","gco_companies_contact_fon":"","gco_companies_contact_email":"info@modag.net","gco_companies_contact_website_url":"https:\/\/www.modag.net","gco_companies_contact_website_link_text":"www.modag.net","gco_companies_contact_street":"Am Klopferspitz 19","gco_companies_contact_zip":"82152","gco_companies_contact_city":"Planegg\/Martinsried","gco_companies_contact_country":"Germany","gco_companies_info_business_area":"Drug Discovery, Product Developer","_links":{"self":[{"href":"https:\/\/www.izb-online.de\/en\/wp-json\/wp\/v2\/gco_companies\/1645","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.izb-online.de\/en\/wp-json\/wp\/v2\/gco_companies"}],"about":[{"href":"https:\/\/www.izb-online.de\/en\/wp-json\/wp\/v2\/types\/gco_companies"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.izb-online.de\/en\/wp-json\/wp\/v2\/media\/1644"}],"wp:attachment":[{"href":"https:\/\/www.izb-online.de\/en\/wp-json\/wp\/v2\/media?parent=1645"}],"wp:term":[{"taxonomy":"company-categories","embeddable":true,"href":"https:\/\/www.izb-online.de\/en\/wp-json\/wp\/v2\/company-categories?post=1645"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}